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Antigenic Specificity | Human CD307c/FcRL3 |
Clone | H5/FcRL3 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, κ |
Format | purified, low endotoxin, azide-free |
Size | 1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ultra-LEAF™ Purified anti-human CD307c/FcRL3. CD307c is a type 1 transmembrane glycoprotein in the FcRL family of the Ig gene superfamily that is conserved in humans and not found in mice. It is expressed on NK cells, T cell, regulatory T cell, B cell and plasma cell subsets. Intracellular ITAM and ITIM motifs in conjunction with extracellular Ig domains are thought to play a role in the regulation of immune response, and autoimmune function. Impairment of normal FcRL3 function has been linked to systemic lupus erythematosus, rheumatoid art |
Immunogen | FcRL3 full length expression plasmid DNA, followed by cell boost using transiently transfected cells with the same plasmid. |
Other Names | Fc receptor-like 3 (FCRL3), Immune receptor translocation-associated protein 3 (IRTA3), SH2 domain-containing phosphatase anchor protein 2 (SPAP2), IFGP family protein 3 (IFGP3) |
Gene, Accession # | Gene ID: 115352 |
Catalog # | 374404 |
Price | $715 |
Order / More Info | Human CD307c/FcRL3 Antibody from BIOLEGEND |
Product Specific References | n/a |