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Antigenic Specificity | Human TCR Vα24-Jα18 (iNKT cell) |
Clone | 6B11 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | Brilliant Violet 605™ conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Brilliant Violet 605™ anti-human TCR Vα24-Jα18 (iNKT cell). Encoded by the TCR Vα24-Jα18 germline configuration, Vα24-JαQ is expressed on a subset of NKT cells, namely invariant NKT (iNKT). Vα24-JαQ TCR interacts with the glycolipid loaded MHC class 1b molecule CD1d, inducing activation and subsequent cytokine production. iNKT cells have been implicated in immune regulation, tumor surveillance, and host response to pathogens. While iNKT cells occur at low frequency in the blood, assorted chemokines contribute to their tissue homing potential. |
Immunogen | n/a |
Other Names | TCR Vα24-Jα18, TCR Vα24-JαQ, invariant NKT cell, iNKT |
Gene, Accession # | Gene ID: 28659 |
Catalog # | 342930 |
Price | $435 |
Order / More Info | Human TCR Vα24-Jα18 (iNKT cell) Antibody from BIOLEGEND |
Product Specific References | n/a |