Mouse CD357 (GITR) Antibody from BIOLEGEND

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Antigenic SpecificityMouse CD357 (GITR)
CloneDTA-1
Host SpeciesRat
Reactive Speciesmouse
IsotypeIgG2b, κ
Formatphycoerythrin (PE) conjugate
Size25 µg
Concentrationn/a
ApplicationsFlow Cytometry (FC)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionPE anti-mouse CD357 (GITR). GITR (glucocorticoid-induced TNFR-related gene) is a member of the TNF receptor superfamily, also known as TNFRSF18 and AITR (in humans). It is expressed at low levels on resting T lymphocytes and at high levels on CD25 CD4 Tregs. The expression of GITR on T cells can be upregulated upon activation. Interaction of GITR with its ligand (GITRL) has been demonstrated to augment T cell activation, proliferation, cytokine production as well as MAPKs and NF-κB activation, and abrogate the inhibitory
ImmunogenMouse CD25+ CD4+ T cells
Other NamesGlucocorticoid-induced TNFR -related gene, TNFRSF18
Gene, Accession #Gene ID: 21936
Catalog #126309
Price$110
Order / More InfoMouse CD357 (GITR) Antibody from BIOLEGEND
Product Specific ReferencesPubMed: 23892569, 29136509, 29221730, 31167140, 31027998, 29221730
BIOLEGEND
BIOLEGEND
BIOLEGEND
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San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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