Bcl11b Antibody from BIOLEGEND

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Antigenic SpecificityBcl11b
Clone25B6
Host SpeciesRat
Reactive Specieshuman
IsotypeIgG2a
Formatpurified
Size25 µg
Concentrationn/a
ApplicationsWestern Blot (WB), ICC, ChIP, IHC-P
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DescriptionPurified anti-Bcl11b. The transcription factor Bcl11b is expressed in thymus, mainly T cells. It is indispensable for T lineage development. When Bcl11b was deleted, T cells from all developmental stages acquired NK cell properties and concomitantly lost or decreased T cell-associated gene expression. These induced T-to-natural killer (ITNK) cells, which were morphologically and genetically similar to conventional NK cells, killed tumor cells in vitro, and effectively prevented tumor metastasis in vivo. Therefore, IT
ImmunogenHuman Bcl11b
Other NamesB-cell CLL/lymphoma 11B (zinc finger protein), CTIP2, B-cell lymphoma/leukemia 11B
Gene, Accession #Gene ID: 64919
Catalog #650601
Price$176
Order / More InfoBcl11b Antibody from BIOLEGEND
Product Specific ReferencesPubMed: 23671688, 30840538, 28299779
BIOLEGEND
BIOLEGEND
BIOLEGEND
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San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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