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Antigenic Specificity | SMAD1 Phospho (S463/S465)/SMAD9 (S465/S467) |
Clone | A17019A |
Host Species | Mouse |
Reactive Species | mouse, human |
Isotype | IgG1, λ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-SMAD1 Phospho (S463/S465)/SMAD9 (S465/S467). SMAD1 and SMAD9 (SMAD8) are members of SMAD family, whose members play a critical role in signal transduction from the TGF-β receptor kinases. Activation of these receptors results in phosphorylation of SMAD1 and SMAD9 at a C-terminal SSXS motif (Ser463/Ser465 in SMAD1; Ser465/Ser467 in SMAD9), leading to dimerization with the coactivator SMAD4. The SMAD1-4 complex is translocated to the nucleus where it induces expression of target genes involved in differentiation, self-renewal, proliferation, |
Immunogen | n/a |
Other Names | Mothers against decapentaplegic homolog 1, JV4-1, Mad-related protein 1 |
Gene, Accession # | Gene ID: 4086, 4093 |
Catalog # | 610402 |
Price | $265 |
Order / More Info | SMAD1 Phospho (S463/S465)/SMAD9 (S465/S467) Antibody from BIOLEGEND |
Product Specific References | n/a |