Human DKK-1 Antibody from BIOLEGEND

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Antigenic SpecificityHuman DKK-1
CloneW19277H
Host SpeciesRat
Reactive Specieshuman
IsotypeIgG2a, κ
Formatbiotin conjugate
Size50 µg
Concentrationn/a
ApplicationsDirect ELISA
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DescriptionBiotin anti-human DKK-1. DKK-1 (Dickkopf related protein 1) is a member of the Dickkopf family of proteins that include DKK-1, -2, -3, -4, and Soggy. DKK-1 was discovered by its ability to block Wnt signaling during early Xenopus embryogenesis. DKK-1 antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt proteins. DKK-1 forms a ternary complex with LRP5/6 and the transmembrane protein Kremen1/2, promoting internalization of LRP5/6 and down regulation of Wnt signaling. DKK-1 contains two conserved
ImmunogenHuman Recombinant DKK-1 Protein
Other NamesDickkopf-related protein 1, DKK1, Dickkopf WNT signaling pathway inhibitor 1
Gene, Accession #Gene ID: 22943
Catalog #617053
Price$265
Order / More InfoHuman DKK-1 Antibody from BIOLEGEND
Product Specific Referencesn/a
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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