Edit |   |
---|---|
Antigenic Specificity | Human EGFR |
Clone | AY13 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | PE-Cyanine7 conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE/Cyanine7 anti-human EGFR. Epidermal growth factor receptor (EGFR) is a transmembrane glycoprotein and member of the protein kinase superfamily that regulates cell growth and differentiation. EGFR binds EGF, TGF-α, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30, and vaccinia virus growth factor - all members of the EGF family. Ligand binding induces EGFR dimerization and autophosphorylation, initiating the MAPK, Akt, and JNK signaling pathways. EGFR is expressed by epithelial and endothelial cell |
Immunogen | Non-small cell lung cancer (NSCLC) cell line NCI-H322 |
Other Names | Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, HER1 |
Gene, Accession # | Gene ID: 1956 |
Catalog # | 352910 |
Price | $382 |
Order / More Info | Human EGFR Antibody from BIOLEGEND |
Product Specific References | PubMed: 30889382, 31548346 |