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Antigenic Specificity | APP C-Terminal Fragment |
Clone | C1/6.1 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | purified, azide-free |
Size | 25 µL |
Concentration | n/a |
Applications | Western Blot (WB), ICC, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified (azide-free) anti-APP C-Terminal Fragment. APP functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. It is involved in cell mobility and transcription regulation through protein-protein interactions and cleaved either by alpha-secretase, beta-secretase or theta-secretase, leading to generation and extracellular release of soluble APP peptides, S-APP-alpha and S-APP-beta, and the retention of corresponding membrane-anchored C-term |
Immunogen | This antibody was raised against the conserved carboxyl-terminal 20 residues of APP (residues 676-695 of APP695). |
Other Names | AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Amyloid beta A4 protein, preA4, protease nexin-II, peptidase nexin-II, beta-amyloid peptide, alzheimer disease amyloid protein, cerebral vascular amyloid peptide, APP, Amyloid Precursor Protein |
Gene, Accession # | Gene ID: 351 |
Catalog # | 802803 |
Price | $112 |
Order / More Info | APP C-Terminal Fragment Antibody from BIOLEGEND |
Product Specific References | PubMed: 26080426, 20080541, 27563067, 29348617, 29021256, 29149631, 29539399, 29724785, 30590039, 30617153, 28559572, 30590039, 32019490, 32395715, 28815510, 28362033, 30980041, 33028637, 33440141, 33891876, 34133918 |