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Antigenic Specificity | Mouse GITR Ligand |
Clone | YGL 386 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1, κ |
Format | phycoerythrin (PE) conjugate |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE anti-mouse GITR Ligand. GITR ligand (GITRL) is a member of the TNF superfamily, also known as TNFSF18 or TL6. It is expressed on B cells, macrophages, dendritic cells and endothelial cells. The expression of GITRL on dendritic cell surface can be transiently up-regulated and then rapidly down-regulated by LPS stimulation. GITRL binds to its receptor, GITR, to co-stimulate T cell activation, proliferation, and cytokine production, and inhibit the suppressive functions of CD4 CD25 Treg cells, as well as induce macrophag |
Immunogen | Recombinant mouse GITRL protein and Transfected cells |
Other Names | AITRL, TNFSF18, TL6, GITRL |
Gene, Accession # | Gene ID: 240873 |
Catalog # | 120305 |
Price | $122 |
Order / More Info | Mouse GITR Ligand Antibody from BIOLEGEND |
Product Specific References | PubMed: 22368274, 28440511, 31533045, 31533045 |