NLRP2 Antibody from BIOLEGEND

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Antigenic SpecificityNLRP2
Clone8F10B51
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, κ
Formatpurified
Size100 µg
Concentrationn/a
ApplicationsWestern Blot (WB), ICC
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DescriptionPurified anti-NLRP2. NLRP2, also known as NALP2 or PAN1, is a member of the pyrin domain-containing NLR protein (NLRP) family. The NLR proteins interact with ASC via the conserved pyrin domain, which results in the activation of caspase-1 and maturation of the pro-inflammatory cytokines IL-1β and IL-18. NLRP2 is also involved in the formation of the inflammasome and caspase-1 activation. NLRP2 negatively regulates NFκB activation, which is induced by TNF-α, through inhibiting NFKBIA degradation. In addition, NLRP2 i
ImmunogenPartial NLRP2 recombinant protein (60-192 aa) expressed in E. coli.
Other NamesNACHT, LRR and PYD domains-containing protein 2, Nucleotide-binding site protein 1 (NBS-1), NBS1, PYRIN domain and NACHT domain-containing protein 1 (PAN1), PYRIN-containing APAF1-like protein 2 (PYPAF2)
Gene, Accession #Gene ID: 55655
Catalog #673902
Price$265
Order / More InfoNLRP2 Antibody from BIOLEGEND
Product Specific Referencesn/a
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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