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Antigenic Specificity | NLRP2 |
Clone | 8F10B51 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-NLRP2. NLRP2, also known as NALP2 or PAN1, is a member of the pyrin domain-containing NLR protein (NLRP) family. The NLR proteins interact with ASC via the conserved pyrin domain, which results in the activation of caspase-1 and maturation of the pro-inflammatory cytokines IL-1β and IL-18. NLRP2 is also involved in the formation of the inflammasome and caspase-1 activation. NLRP2 negatively regulates NFκB activation, which is induced by TNF-α, through inhibiting NFKBIA degradation. In addition, NLRP2 i |
Immunogen | Partial NLRP2 recombinant protein (60-192 aa) expressed in E. coli. |
Other Names | NACHT, LRR and PYD domains-containing protein 2, Nucleotide-binding site protein 1 (NBS-1), NBS1, PYRIN domain and NACHT domain-containing protein 1 (PAN1), PYRIN-containing APAF1-like protein 2 (PYPAF2) |
Gene, Accession # | Gene ID: 55655 |
Catalog # | 673902 |
Price | $265 |
Order / More Info | NLRP2 Antibody from BIOLEGEND |
Product Specific References | n/a |