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Antigenic Specificity | TRAF1 |
Clone | W15137A |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-TRAF1. TNF Receptor Associated Factor 1 (TRAF1) is a member of the TRAF protein family, which mediates the downstream signaling of the TNFR superfamily, such as CD40, CD30, TNFR1 and TNFR2. Upon stimulation of TNF-α, TRAF1 forms a heterodimer with TRAF2 and subsequently activates MAPK/JNK and NFkB pathways. The TRAF1/TRAF2 complex also interacts with apoptosis inhibitor protein IAPs and mediates the anti-apoptotic signaling from TNF receptor. This heterodimer is part of the antiapoptotic E3 ubiquitin-p |
Immunogen | Partial human TRAF1 recombinant protein (1-182 a.a.) expressed in E. coli. |
Other Names | TNF receptor associated factor 1, EBI6 |
Gene, Accession # | Gene ID: 7185 |
Catalog # | 689802 |
Price | $253 |
Order / More Info | TRAF1 Antibody from BIOLEGEND |
Product Specific References | n/a |