Description | PE anti-human CD4. CD4, also known as T4, is a 55 kD single-chain type I transmembrane glycoprotein expressed on most thymocytes, a subset of T cells, and monocytes/macrophages. CD4, a member of the Ig superfamily, recognizes antigens associated with MHC class II molecules and participates in cell-cell interactions, thymic differentiation, and signal transduction. CD4 acts as a primary receptor for HIV, binding to HIV gp120. CD4 has also been shown to interact with IL-16. |
Product Specific References | PubMed: 22397822, 23861553, 24868087, 25246534, 27539532, 27815422, 30632307, 30645648, 28817184, 30753169, 31533030, 27881659, 29164066, 32313722, 31030958, 31969707, 31888669, 33103593, 32628964, 32518350, 31753920, 33789089, 33910003 |