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Antigenic Specificity | Mouse Siglec H |
Clone | 551 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG1, κ |
Format | allophycocyanin (APC) conjugate |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | APC anti-mouse Siglec H. The Siglec-H is a member of CD33-related Siglec family which mostly expressed in the innate immune system. Siglec-H is reported to be specifically expressed on plasmacytoid dendritic cells. Siglec-H depends on adaptor protein DAP 12 (DNAX-activating protein of 12 kD) for surface expression and signal transduction. Cross-linking with this antibody can selectively inhibit interferon-alpha production by IPCs following TLR9 ligation. |
Immunogen | Siglec-H-Fc recombinant fusion protein |
Other Names | Sialic acid-binding immunoglobulin-like lectin |
Gene, Accession # | Gene ID: 233274 |
Catalog # | 129611 |
Price | $149 |
Order / More Info | Mouse Siglec H Antibody from BIOLEGEND |
Product Specific References | PubMed: 27926930, 29166591, 31825848, 32117252, 31645721, 33067530, 32668198, 33357409 |