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Antigenic Specificity | Human/Mouse CD3ε (activation epitope) |
Clone | APA1/1 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1, κ |
Format | phycoerythrin (PE) conjugate |
Size | 25 tests |
Concentration | n/a |
Applications | Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE anti-human/mouse CD3ε (activation epitope). The CD3ε chain of the CD3-TCR complex is a type I membrane protein that undergoes conformational change following ligation of the TCR-CD3 complex. This conformational change leads to exposure of the proline rich sequence in CD3ε and results in recruitment of Nck. It is expressed by all mature T cells and forms a heteromeric complex with CD3 α/β or γ/δ and ζ chains. It is important in T cell development, and deficiency of this gene has been associated with severe immunodeficiency. |
Immunogen | Purified denatured CD3 proteins from human thymus |
Other Names | CD3e molecule, epsilon (CD3-TCR complex), CD3e antigen, CD3 epsilon |
Gene, Accession # | Gene ID: 916 |
Catalog # | 362703 |
Price | $86 |
Order / More Info | Human/Mouse CD3ε (activation epitope) Antibody from BIOLEGEND |
Product Specific References | n/a |