TNF-α Antibody from BIOLEGEND

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Antigenic SpecificityTNF-α
Clonepolyclonal
Host SpeciesGoat
Reactive Speciesmouse, rat
Isotypen/a
Formatbiotin conjugate
Size50 µg
Concentrationn/a
ApplicationsELISA Detection
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DescriptionBiotin anti-mouse/rat TNF-α. TNF-α is secreted by macrophages, monocytes, neutrophils, T-cells (principally CD4+), and NK-cells. Many transformed cell lines also secrete TNF-α. Monomeric mouse TNF-α is 156 amino acid protein (N-glycosylated) with a reported molecular weight of 17.5 kD protein. TNF-α forms multimeric complexes; stable trimers are most common in solution. A 26 kD membrane form of TNF-α has also been described. TNF-α binding to surface receptors elicits a wide array of biologic activities including: cytolysis and cytostasis of many tumor cell lines in vitro, hemorraghic necrosis of tumors in vivo, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils.
ImmunogenRecombinant mouse TNF-α
Other NamesTumor necrosis factor-α (TNF alpha), Cachectin, Necrosin, Macrophage cytotoxic factor (MCF), Differentiation inducing factor (DIF), TNFSF-2, TNFSF2, TNFa
Gene, Accession #Gene ID: 21926
Catalog #516003
Price$95
Order / More InfoTNF-α Antibody from BIOLEGEND
Product Specific Referencesn/a
BIOLEGEND
BIOLEGEND
BIOLEGEND
9727 Pacific Heights Blvd.
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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http://www.biolegend.com

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