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Antigenic Specificity | ERCC1 |
Clone | W20045D |
Host Species | Rat |
Reactive Species | human, mouse |
Isotype | IgG2b, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), IHC-P, ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-ERCC1. ERCC1, also referred to as Excision Repair Cross-Complementation Group 1, is a component of the nucleotide excision repair pathway. ERCC1 forms a heterodimer with XPF endonuclease to catalyze the 5' incision in the process of excising a DNA lesion. ERCC1 also works with SLX4 in homology direct repair of double strand breaks and in the repair of crosslinks. Mutations in ERCC1 play a role in carcinogenesis due to genome instability, and elevated expression of ERCC1 is predictive of resistance to p |
Immunogen | Partial recombinant human ERCC1 protein |
Other Names | Excision Repair Cross-Complementation Group 1, ERCC excision repair 1, endonuclease non-catalytic subunit, RAD10 |
Gene, Accession # | Gene ID: 2067 |
Catalog # | 947502 |
Price | $293 |
Order / More Info | ERCC1 Antibody from BIOLEGEND |
Product Specific References | n/a |