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Antigenic Specificity | Human CD117 (c-kit) |
Clone | A3C6E2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-human CD117 (c-kit). CD117 is a 145 kD protein tyrosine kinase also known as c-kit. It is a receptor for stem cell factor or c-kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemic cells (AML). CD117 binding of c-kit ligand induces phosphorylation of CD117, and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells. The A3C6E2 |
Immunogen | MOLM-1 megakaryocitic cell line |
Other Names | Stem cell factor receptor, c-kit, mast cell growth factor receptor, steel factor receptor |
Gene, Accession # | Gene ID: 3815 |
Catalog # | 323402 |
Price | $176 |
Order / More Info | Human CD117 (c-kit) Antibody from BIOLEGEND |
Product Specific References | n/a |