Edit |   |
---|---|
Antigenic Specificity | Human CD125 (IL-5Rα) |
Clone | S20015E |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | phycoerythrin (PE) conjugate |
Size | 25 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE anti-human CD125 (IL-5Rα). CD125, also known as IL5 receptor α-chain, is a 60 kD type I transmembrane protein that binds IL-5 and associates in a heterodimer with the signal-transducing β subunit CD131 to form the IL-5 receptor. The affinity of CD125 for IL-5 is increased when is associated with CD131. The cytoplasmic region of CD125 activates the JAK2/STAT5 pathway and the kinase Btk. CD125 is expressed by eosinophils, basophils, mast cells, B1 cells and a subset of resting B2 cells and have a central role in the differe |
Immunogen | Mouse IL-5Rα transfected cells |
Other Names | IL5RA, IL5R, CDw125, HSIL5R3 |
Gene, Accession # | Gene ID: 3568 |
Catalog # | 384703 |
Price | $165 |
Order / More Info | Human CD125 (IL-5Rα) Antibody from BIOLEGEND |
Product Specific References | n/a |