Notch 1 Antibody from BIOLEGEND

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Antigenic SpecificityNotch 1
ClonemN1A
Host SpeciesMouse
Reactive Speciesmouse, human
IsotypeIgG1, κ
Formatphycoerythrin (PE) conjugate
Size100 µg
Concentrationn/a
ApplicationsIntracellular Staining for Flow Cytometry (ICFC)
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DescriptionPE anti-Notch 1. Notch1, also known as neurogenic locus notch homolog protein 1, is a large >270 kD protein that functions as a receptor for the membrane ligands Jagged1, Jagged2 and Delta1 to regulate cell fate decisions. Upon ligand activation, the transmembrane Notch1 receptor is cleaved by TNF-alpha converting enzyme (TACE) to produce a membrane-associated intermediate fragment (NEXT). This fragment is further cleaved by presenilin-dependent gamma secretase to release a notch-derived peptide containing the i
ImmunogenNotch1 GST fusion protein
Other NamesNeurogenic locus notch homolog protein 1, Notch-1
Gene, Accession #Gene ID: 4851
Catalog #629106
Price$202
Order / More InfoNotch 1 Antibody from BIOLEGEND
Product Specific ReferencesPubMed: 26766040, 28112644
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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