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Antigenic Specificity | PIEZO1 |
Clone | W17241A |
Host Species | Rat |
Reactive Species | human, mouse |
Isotype | IgG2b, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | IHC-P, Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-PIEZO1. PIEZO1 and its paralog PIEZO2 are members of a non-selective cationic mechanosensitive channel family first discovered in a neuronal cell line through mechanical stimulation. It responds to mechanical forces such as static pressure, shear stress, and membrane stretch events by allowing the efflux of calcium ions from the ER lumen into the cytosol. The increase in cytosolic calcium results in phosphorylation of ERK1/2 and a commensurate induction of downstream mitotic genes, and can also promote |
Immunogen | Partial recombinant human PIEZO1 protein |
Other Names | PIEZO Type Mechanosensitive Ion Channel Component 1; Membrane Protein Induced By Beta-Amyloid Treatment; FAM38A; Mib; KIAA023; LMPH3; DHS |
Gene, Accession # | Gene ID: 9780 |
Catalog # | 602752 |
Price | $293 |
Order / More Info | PIEZO1 Antibody from BIOLEGEND |
Product Specific References | n/a |