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Antigenic Specificity | Mouse CD272 (BTLA) |
Clone | 8F4 |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG1, κ |
Format | phycoerythrin (PE) conjugate |
Size | 25 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PE anti-mouse CD272 (BTLA). B and T lymphocyte attenuator (BTLA) is an Ig superfamily coinhibitory receptor with structural similarity to programmed cell death 1 (PD-1) and CTLA-4. BTLA is expressed on B cells, T cells, macrophages, dendritic cells, NKT cells, and NK cells. Engagement of BTLA by its ligand Herpes Virus Entry Mediator (HVEM) is critical for negatively regulating immune response. The absence of BTLA with HVEM inhibitory interactions leads to increased experimental autoimmune encephalomyelitis severity, enhan |
Immunogen | C57BL/6 BTLA Ig domain protein in CFA |
Other Names | BTLA, B and T lymphocyte attenuator |
Gene, Accession # | Gene ID: 208154 |
Catalog # | 134803 |
Price | $134 |
Order / More Info | Mouse CD272 (BTLA) Antibody from BIOLEGEND |
Product Specific References | PubMed: 31189114, 31189114 |