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Antigenic Specificity | Mcl-1 |
Clone | W16014A |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Mcl-1. Myeloid cell leukemia sequence 1 (MCL-1), also known as Bcl2-L-3, is a member of the pro-survival BCL-2 family of apoptotic regulatory proteins. MCL-1 plays a crucial role in the survival and development of various cell types by binding to proapoptotic proteins and inhibiting the mitochondrial apoptotic pathway. Unlike Bcl-2 and Bcl-xL, MCL-1 lacks a BH4 domain and contains an N-terminal PEST region with specific sequences for ubiquitination, phosphorylation, and caspase cleavage sites, which ar |
Immunogen | Full length mouse MCL-1 recombinant protein expressed in E. coli. |
Other Names | Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3 (BCL2-L-3), Bcl-2-related protein EAT/mcl1, |
Gene, Accession # | Gene ID: 4170 |
Catalog # | 695702 |
Price | $276 |
Order / More Info | Mcl-1 Antibody from BIOLEGEND |
Product Specific References | n/a |