Edit |   |
---|---|
Antigenic Specificity | Human CD230 (Prion) |
Clone | 3F4 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | allophycocyanin (APC) conjugate |
Size | 25 tests |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | APC anti-human CD230 (Prion). Prions cause neurodegenerative disease by aggregating extracellularly within the central nervous system which disrupt the normal tissue structure. This disruption is characterized by ?holes? in the tissue with resultant spongy architecture. Two conformational isoforms exist, the normal cellular isoform (PrPC) and the infectious, scrapie isoform (PrPSC). Other histological changes include astrogliosis and the absence of an inflammatory reaction. Neurodegenerative symptoms can include convulsions, |
Immunogen | n/a |
Other Names | Major prion protein, p27-30, CD230 antigen, prion protein PrP, prion-related protein |
Gene, Accession # | Gene ID: 5621 |
Catalog # | 800315 |
Price | $149 |
Order / More Info | Human CD230 (Prion) Antibody from BIOLEGEND |
Product Specific References | n/a |