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Antigenic Specificity | ARTC2 Nanobody) |
Clone | S+16a |
Host Species | Recombinant Llama |
Reactive Species | mouse |
Isotype | VH Ig |
Format | unconjugated |
Size | 250 µg |
Concentration | n/a |
Applications | Block |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Treg-Protector™ (anti-ARTC2 Nanobody). ARTC2, also known as ART2.2, is a 35 kD, GPI-anchored, and cell surface ADP-ribosyltransferase that is highly expressed by regulatory T cells (Tregs) and natural killer T (NKT) cells. ARTC2 is enzymatically active at 4°C. Through the ribosylation of the ion channel P2X7, ARTC2 mediates NAD -induced cell death (NICD) and the proteolytic shedding of CD27 and CD62L. Blocking the activity ARTC2 with Treg-Protector™ improves the recovery of Tregs and NKT cells during their isolation from lymphatic an |
Immunogen | Expression vector encoding full length mouse ARTC2. |
Other Names | ART2.2, Art2b, Art, Rt6, Rt-6, Ly92b, Rt6-2 |
Gene, Accession # | Gene ID: 11872 |
Catalog # | 149801 |
Price | $347 |
Order / More Info | ARTC2 Nanobody) Antibody from BIOLEGEND |
Product Specific References | PubMed: 31308092, 32640257 |