LAT Antibody from BIOLEGEND
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| Antigenic Specificity | LAT |
| Clone | LAT1111 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1, κ |
| Format | purified |
| Size | 100 µg |
| Concentration | n/a |
| Applications | Western Blot (WB), Intracellular Staining for Flow Cytometry (ICFC), IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Purified anti-LAT. LAT (linker for activation of T-cells) is a 36 kD phospho-tyrosine adaptor protein containing SH2 domains and a CVRC motif. Two LAT isoforms have been reported with approximate molecular weights of 36 kD and 38 kD. LAT is localized to lipid rafts, and is also a potential type III transmembrane protein, thought to be expressed in the juxtanuclear intracellular compartment. LAT links TCR engagement to Ras-MAPK activation, Ca2 flux, IL-2 expression and is required for T-cell development. LAT is ph |
| Immunogen | Partial recombinant protein (cytoplasmic domain of human LAT) |
| Other Names | Linker for activation of T-cells, 36 kD phospho-tyrosine adaptor protein |
| Gene, Accession # | Gene ID: 27040 |
| Catalog # | 623902 |
| Price | $218 |
| Order / More Info | LAT Antibody from BIOLEGEND |
| Product Specific References | PubMed: 32160548 |
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