SLP76 Phospho (Ser376) Antibody from BIOLEGEND
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| Antigenic Specificity | SLP76 Phospho (Ser376) |
| Clone | A18001A |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG1, κ |
| Format | purified |
| Size | 100 µg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Purified anti-SLP76 Phospho (Ser376). SLP76 is a cytosolic adapter protein that functions as a substrate in the T cell receptor (TCR) activation pathway. Upon TCR engagement, SLP76 is phosphorylated on multiple residues, resulting in the protein being tranlocated to the plasma membrane and facilitating the assembly of a multi-subunit complex comprised of Vav1, Nck, ITK, and PLCγ1. SLP76 also plays an essential role in normal T cell development.SLP76 also represents a negative regulatory node in the TCR activation pathway. Following |
| Immunogen | Synthetic human SLP76 peptide containing phosphorylated Ser376 |
| Other Names | LCP2, Lymphocyte cytosolic protein 2, SH2 domain-containing leukocyte protein of 76 kDa, SLP-76 tyrosine phosphoprotein |
| Gene, Accession # | Gene ID: 3937 |
| Catalog # | 667102 |
| Price | $265 |
| Order / More Info | SLP76 Phospho (Ser376) Antibody from BIOLEGEND |
| Product Specific References | n/a |
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