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Antigenic Specificity | Human/Mouse ZAP-70 |
Clone | 1E7.2 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Intracellular Staining for Flow Cytometry (ICFC), Western Blot (WB), IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-human/mouse ZAP-70. ZAP-70 is a 70 kD protein tyrosine kinase associated with the zeta chain of the T cell receptor. It is expressed in T cells and NK cells and has been shown to be involved in T cell signaling. Defects in ZAP-70 have been linked to selective T cell defects. The ZAP-70 kinase undergoes multiple phosphorylation events after T cell receptor engagement and interacts with a number of proteins involved in signal transduction. Recently, ZAP-70 has been identified as an important prognostic marker in B-ce |
Immunogen | GST-fusion protein corresponding to residues 282-307 of human ZAP-70 |
Other Names | Zeta chain associated protein kinase, SYK related tyrosine kinase |
Gene, Accession # | Gene ID: 22637, 7353 |
Catalog # | 313402 |
Price | $183 |
Order / More Info | Human/Mouse ZAP-70 Antibody from BIOLEGEND |
Product Specific References | PubMed: 19240243, 23225883, 32437509 |