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Antigenic Specificity | Mouse CD103 |
Clone | QA17A24 |
Host Species | Recombinant Mouse |
Reactive Species | mouse |
Isotype | IgG1, κ |
Format | PerCP-Fire™ 806 conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PerCP/Fire™ 806 anti-mouse CD103 Recombinant. CD103 is a type I transmembrane glycoprotein known as αE integrin or Integrin αIEL chain. It belongs to the integrin family and is primarily found on intestinal intraepithelial lymphocytes (IEL). CD103 is also expressed on a subpopulation of lamina propria T cells, epithelial dendritic cells, lamina propria-derived dendritic cells, and a small subset of peripheral lymphocytes. T regulatory cells express high level of CD103. The CD103 expression on lymphocytes can be induced upon activation and TGF-β stimulation. In association with integrin β7, CD103 is expressed as αE/β7 heterodimer. Mature CD103 protein can be cleaved into 2 chains, a 150 kD (C-terminal) chain and a 25 kD (N-terminal) chain, which remain linked by disulfide bonds. CD103 binds to E-cadherin and mediates homing of lymphocytes to the intestinal epithelium. |
Immunogen | Mouse intestinal intraepithelial lymphocytes |
Other Names | Integrin αIEL chain, Integrin αE chain, αE integrin, ITGAE |
Gene, Accession # | Gene ID: 16407 |
Catalog # | 156926 |
Price | $390 |
Order / More Info | Mouse CD103 Antibody from BIOLEGEND |
Product Specific References | n/a |