Edit |   |
---|---|
Antigenic Specificity | SHC1 |
Clone | O91H8 |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Western Blot (WB), IP, ICC, IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-SHC1. SHC1 is a ubiquitously expressed adaptor protein involved in receptor tyrosine kinase signaling including the activation of the RAS/Raf/MAPK pathway. Three isoforms of SHC1 (p66, p52, p46) have been described, each with unique cellular functions. SHC1 has an SH2 domain and a protein tyrosine phosphate binding (PTB) domain, which recognize activated receptor tyrosine kinases. Tyrosine residues located in the CH1 domain of SHC1 are phosphorylated by tyrosine kinases and serve as docking sites for |
Immunogen | Full length recombinant human SHC1 protein |
Other Names | SHC Adaptor Protein 1, SHC-Transforming Protein 1, SHC-Transforming Protein 3, SHC-Transforming Protein A, SH2 Domain Protein C1, SHCA, SHC, SHC (Src Homology 2 Domain Containing) Transforming Protein 1 |
Gene, Accession # | Gene ID: 6464 |
Catalog # | 669701 |
Price | $101 |
Order / More Info | SHC1 Antibody from BIOLEGEND |
Product Specific References | n/a |