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Antigenic Specificity | Mouse Tim-4 |
Clone | RMT4-54 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | purified |
Size | 200 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC), FA, Block |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-mouse Tim-4. Tim-4 is a transmembrane protein known as T cell immunoglobulin and mucin domain containing protein-4. It is expressed on antigen-presenting cells and not on T cells. Tim-4 binds to Tim-1 to promote T cell proliferation by enhancing cell division and reducing apoptosis. Tim-4 bind to phosphatidylserine through its FG-CC' binding cleft in the N-terminal IgV domain to facilitate the clearance of apoptotic cells or bodies. |
Immunogen | Mouse TIM4-Ig fusion protein |
Other Names | T cell immunoglobulin and mucin domain containing protein-4 |
Gene, Accession # | Gene ID: 276891 |
Catalog # | 130002 |
Price | $293 |
Order / More Info | Mouse Tim-4 Antibody from BIOLEGEND |
Product Specific References | PubMed: 23319738, 32574624, 33440159 |