Granzyme B Antibody from BIOLEGEND

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Antigenic SpecificityGranzyme B
CloneM3304B06
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1, κ
Formatpurified
Size100 µg
Concentrationn/a
ApplicationsWestern Blot (WB), IHC-P, SB
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DescriptionPurified anti-Granzyme B. Granzyme B is a serine protease that is mainly produced by cytotoxic T cells (CTL) and NK cells. It plays important roles in cytotoxic lymphocyte-mediated apoptosis, chronic inflammation, and impaired wound healing. Granzyme B is packaged in cytoplasmic granules that are exocytosed towards a bound target cell, and subsequently activates multiple protein substrates to induce apoptosis. Perforin facilitates the transfer of Granzyme B into the target cell. Most circulating CD56 CD8- NK cells and a
ImmunogenRecombinant human Granzyme B produced in the 293E cell line.
Other NamesGranzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1, GZMB, CCP1, Asp-ase, CSPB, CTLA-1, CGL-1, CGL1
Gene, Accession #Gene ID: 3002
Catalog #674602
Price$300
Order / More InfoGranzyme B Antibody from BIOLEGEND
Product Specific ReferencesPubMed: 30969166
BIOLEGEND
BIOLEGEND
BIOLEGEND
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P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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