Description | Brilliant Violet 650™ anti-human CD8a. CD8a is a 32-34 kD type I glycoprotein. It forms a homodimer (CD8a/a) or heterodimer (CD8a/b) with CD8b. CD8, also known as T8 and Leu2, is a member of the immunoglobulin superfamily found on the majority of thymocytes, a subset of peripheral blood T cells, and NK cells (which express almost exclusively CD8a homodimers). CD8 acts as a co-receptor with MHC class I-restricted T cell receptors in antigen recognition and T cell activation, and has been shown to play a role in thymic differentiation. |
Product Specific References | PubMed: 25980035, 27409590, 27342848, 30388456, 30267761, 31500597, 30388456, 31875555, 31601268, 32553157, 31924475, 32473127, 31851923, 31641163, 32986722, 32661393, 32966788, 32498431, 32132233, 33521695, 33592174 |