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Antigenic Specificity | Vinculin |
Clone | W18245A |
Host Species | Rat |
Reactive Species | human, mouse |
Isotype | IgG2a, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Western Blot (WB), ICC, IP, IHC-P |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Vinculin. Vinculin is a filamentous actin (F-actin) binding protein that was originally described as a critical component of focal adhesion plaques. It plays an important role in the transmission of mechanical forces, stabilization of cell-cell junctions via a direct interaction with α-catenin, and linking of integrins to the actin cytoskeleton. Loss of Vinculin protein expression contributes to metastatic phenotypes in cancer tissue due to loss of cell-cell adhesion. Vinculin has been isolated from prost |
Immunogen | Partial recombinant human Vinculin protein |
Other Names | Metavinculin, MV, Epididymis Secretory Sperm Binding Protein, Epididymis Luminal Protein 114 |
Gene, Accession # | Gene ID: 7414 |
Catalog # | 938401 |
Price | $101 |
Order / More Info | Vinculin Antibody from BIOLEGEND |
Product Specific References | n/a |