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Antigenic Specificity | PLCγ1 Phospho (Tyr783) |
Clone | A17025A |
Host Species | Mouse |
Reactive Species | human, mouse |
Isotype | IgG1, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Western Blot (WB), Intracellular Staining for Flow Cytometry (ICFC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-PLCγ1 Phospho (Tyr783). Phospholipase C (PLC) enzymes cleave the phospholipid phosphatidylinositol 4,5-bisphosphate (PIP2) into second messenger molecules inositol 1,4,5-triposphate (IP3) and diacylglycerol (DAG) in response to extracellular stimuli. IP3 causes the release of calcium from the endoplasmic reticulum to begin an intracellular signaling cascade, while DAG activates Protein Kinase C.There are four families of PLCs. PLC gamma (PLCγ) uniquely contains SRC domains SH2 and SH3. Receptor tyrosine kinases interac |
Immunogen | Synthetic peptide from human PLCγ1 phosphorylated at Tyr783 emulsified in CFA. |
Other Names | PLC1, NCKAP3, PLC-II, PLC148 |
Gene, Accession # | Gene ID: 5335 |
Catalog # | 612401 |
Price | $112 |
Order / More Info | PLCγ1 Phospho (Tyr783) Antibody from BIOLEGEND |
Product Specific References | n/a |