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Antigenic Specificity | HMGB1 |
Clone | 3E8 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2b, κ |
Format | peroxidase (HRP) conjugate |
Size | 25 µL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Direct-Blot™ HRP anti-HMGB1. High mobility group protein B1 (HMGB1) belongs to a family of highly conserved proteins that contain HMG box domains. Human HMGB1 is expressed as a 215 amino acid (aa) single chain polypeptide containing three domains: two N-terminal globular, 70 aa positively charged DNA binding domains (HMG boxes A and B), and a negatively charged 30 aa C-terminal region that contains only Asp and Glu. Human HMGB1 is 100% aa identical to canine HMGB1 and 99% aa identical to mouse, rat, bovine and porcine HMGB1 |
Immunogen | Recombinant human HMGB1 with GST tag. A universal T cell epitope from a Mycobacterium tuberculosis antigen was introduced into the C-terminus of HMGB1 to increase the immunogenicity. |
Other Names | High mobility group protein 1, High mobility group protein B1, Sulfoglucuronyl carbohydrate binding protein |
Gene, Accession # | Gene ID: 3146 |
Catalog # | 651411 |
Price | $101 |
Order / More Info | HMGB1 Antibody from BIOLEGEND |
Product Specific References | n/a |