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Antigenic Specificity | Lck Phospho (Tyr505) |
Clone | A17013B |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Lck Phospho (Tyr505). The Src family tyrosine kinase p56Lck (Lck) is a non-receptor tyrosine kinase that plays a critical role in T cell selection and maturation within the thymus, and also in the function of mature T cells. Lck, which is constitutively bound to cytosolic domains of CD4 and CD8 surface receptors, plays an essential role in T cell receptor (TCR) signaling. Engagement of the TCR with peptide antigen-loaded MHC complex results in the recruitment of CD4- and CD8-bound Lck to the TCR/CD3 signaling complex |
Immunogen | Human Lck peptide phosphorylated at Tyr 505. |
Other Names | Leukocyte C-terminal Src kinase, Protein YT16, p56-LCK, T cell-specific protein-tyrosine kinase |
Gene, Accession # | Gene ID: 3932 |
Catalog # | 684301 |
Price | $112 |
Order / More Info | Lck Phospho (Tyr505) Antibody from BIOLEGEND |
Product Specific References | n/a |