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Antigenic Specificity | Human KLRG1 (MAFA) |
Clone | SA231A2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | TotalSeq™-A oligomer conjugate |
Size | 10 µg |
Concentration | n/a |
Applications | PG |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TotalSeq™-A0153 anti-human KLRG1 (MAFA). Killer cell lectin-like receptor subfamily G member 1 (KLRG1) is a 30 kD, type II membrane glycoprotein with one C-type lectin domain and one immunoreceptor tyrosine-based inhibititory motif (ITIM). KLRG1 is expressed by subsets of NK, effector and memory T cells. KLRG1 inhibits cell activation and proliferation, and is a marker of T cell senescence. Binding of KLRG1 to E-, N-, or R- cadherins blocks phosphorylation of Akt and increases the expression of cell cycle inhibitors. |
Immunogen | Human KLRG1-transfected cells |
Other Names | CLEC15A, MAFA-L, MAFA-2F1, MAFA-LIKE, 2F1 |
Gene, Accession # | Gene ID: 10219 |
Catalog # | 367721 |
Price | $369 |
Order / More Info | Human KLRG1 (MAFA) Antibody from BIOLEGEND |
Product Specific References | PubMed: 33835024 |