APP C-Terminal Fragment Antibody from BIOLEGEND

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Antigenic SpecificityAPP C-Terminal Fragment
CloneC1/6.1
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG1
Formatpurified, azide-free
Size200 µL
Concentrationn/a
ApplicationsWestern Blot (WB), ICC, IP
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionPurified (azide-free) anti-APP C-Terminal Fragment. APP functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. It is involved in cell mobility and transcription regulation through protein-protein interactions and cleaved either by alpha-secretase, beta-secretase or theta-secretase, leading to generation and extracellular release of soluble APP peptides, S-APP-alpha and S-APP-beta, and the retention of corresponding membrane-anchored C-term
ImmunogenThis antibody was raised against the conserved carboxyl-terminal 20 residues of APP (residues 676-695 of APP695).
Other NamesAAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Amyloid beta A4 protein, preA4, protease nexin-II, peptidase nexin-II, beta-amyloid peptide, alzheimer disease amyloid protein, cerebral vascular amyloid peptide, APP, Amyloid Precursor Protein
Gene, Accession #Gene ID: 351
Catalog #802801
Price$546
Order / More InfoAPP C-Terminal Fragment Antibody from BIOLEGEND
Product Specific ReferencesPubMed: 26080426, 20080541, 27563067, 29348617, 29021256, 29149631, 29539399, 29724785, 30590039, 30617153, 28559572, 30590039, 32019490, 32395715, 28815510, 28362033, 30980041, 33028637, 33440141, 33891876, 34133918
BIOLEGEND
BIOLEGEND
BIOLEGEND
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