Human CD254 (TRANCE, RANKL) Antibody from BIOLEGEND
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| Antigenic Specificity | Human CD254 (TRANCE, RANKL) |
| Clone | MIH24 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG2b, κ |
| Format | phycoerythrin (PE) conjugate |
| Size | 25 tests |
| Concentration | n/a |
| Applications | Flow Cytometry (FC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | PE anti-human CD254 (TRANCE, RANKL). Human CD254, also known as RANKL, TRANCE, and OPGL, is a type II transmembrane protein in the TNF superfamily that has two forms: a membrane-anchored protein and a secreted protein. Its extracellular domain is related to TRAIL, FasL, and TNF. CD254 is expressed on osteoblasts and activated T cells. It has been implicated in the regulation of the interactions between T cells and dendritic cells. It plays an important role in osteoblast differentiation and bone resorption. CD254 activates JNK and |
| Immunogen | RANKL-transfected L cells |
| Other Names | TRANCE (TNF-related activation-induced cytokine receptor), CD254, RANK-L (receptor activator of NF-κB ligand), OPGL (Osteoprotegerin ligand), SOFA, TNFSF-11 |
| Gene, Accession # | Gene ID: 8600 |
| Catalog # | 347503 |
| Price | $171 |
| Order / More Info | Human CD254 (TRANCE, RANKL) Antibody from BIOLEGEND |
| Product Specific References | PubMed: 29022922, 33554861 |
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