MLKL Antibody from BIOLEGEND

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Antigenic SpecificityMLKL
CloneW17104A
Host SpeciesRat
Reactive Specieshuman
IsotypeIgG2a, κ
Formatpurified
Size25 µg
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionPurified anti-MLKL. MLKL has a four-helix bundle (4HB) domain at the N-terminal and a C-terminal PsKD connected via a two-helix linker. MLKL is important in the necroptotic signaling pathways. During the process, phosphorylated RIP3 (receptor-interacting protein 3) is recruited and phosphorylates MLKL which can induce the oligomerization of MLKL. Oligomerized MLKL translates to the plasma membrane, destroying the membrane integrity and inducing necroptosis. Knockdown or inhibition of MLKL prohibits necrosis. High e
ImmunogenHuman recombinant MLKL Protein (1-193 a.a.) expressed in E. Coli.
Other NamesMLKL, HMLKL
Gene, Accession #Gene ID: 197259
Catalog #666801
Price$101
Order / More InfoMLKL Antibody from BIOLEGEND
Product Specific Referencesn/a
BIOLEGEND
BIOLEGEND
BIOLEGEND
8999 BioLegend Way
San Diego CA 92121
P: (858) 455-9588
P: 1-877-Bio-Legend (246-5343)
F: (858) 455-9587

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