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Antigenic Specificity | Mouse CD357 (GITR) |
Clone | DTA-1 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b, κ |
Format | purified, low endotoxin, azide-free |
Size | 5 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC), IP, FA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Ultra-LEAF™ Purified anti-mouse CD357 (GITR). GITR (glucocorticoid-induced TNFR-related gene) is a member of the TNF receptor superfamily, also known as TNFRSF18 and AITR (in humans). It is expressed at low levels on resting T lymphocytes and at high levels on CD25 CD4 Tregs. The expression of GITR on T cells can be upregulated upon activation. Interaction of GITR with its ligand (GITRL) has been demonstrated to augment T cell activation, proliferation, cytokine production as well as MAPKs and NF-κB activation, and abrogate the inhibitory |
Immunogen | Mouse CD25+ CD4+ T cells |
Other Names | Glucocorticoid-induced TNFR -related gene, TNFRSF18 |
Gene, Accession # | Gene ID: 21936 |
Catalog # | 126323 |
Price | $539 |
Order / More Info | Mouse CD357 (GITR) Antibody from BIOLEGEND |
Product Specific References | n/a |