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Antigenic Specificity | Fumarase |
Clone | 9B1-4E1-8D5 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Western Blot (WB), IHC-P, ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Fumarase. Fumarase, or fumarate hydratase, is a Krebs cycle enzyme that catalyzes the conversion of fumarate to L-malate. A cytosolic isoform of fumarase has been described that is required for arginine metabolism and the urea cycle. Inactivating germline mutations of the FH gene are found in patients with hereditary leiomyomatosis and renal cell cancer syndrome, which predisposes patients to increased risk of developing uterine, cutaneous leiomyomas, and renal cell carcinomas. Mechanistically, elevated f |
Immunogen | Recombinant fragment of human fumarase |
Other Names | Fumarate Hydratase, FH, MCL, HLRCC, MCUL1, FMRD |
Gene, Accession # | Gene ID: 2271 |
Catalog # | 616851 |
Price | $167 |
Order / More Info | Fumarase Antibody from BIOLEGEND |
Product Specific References | n/a |