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Antigenic Specificity | IL-36α |
Clone | O91D11 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-IL-36α. IL-36α is one of the IL-36 cytokines that are part of the IL-1 family. Like other IL-1 family members, IL-36α requires N-terminal processing to gain more potent bioactivity. Currently, the proteases responsible for processing IL-36α are unknown. IL-36α signals through IL-36R/IL-1RAcP, which results in MAPK, Erk1/2, and JNK activation. IL-36α is implicated in skin homeostasis, and it is overexpressed in psoriatic lesional skin. Transgenic mice overexpressing IL-36α in skin have an inflammatory sk |
Immunogen | Full length recombinant human IL-36α (NP_055255) produced in HEK 293T cell line. |
Other Names | IL-36 alpha, IL-1F6, FIL1 epsilon, Interleukin-1 epsilon, IL-1 epsilon |
Gene, Accession # | Gene ID: 27179 |
Catalog # | 676402 |
Price | $229 |
Order / More Info | IL-36α Antibody from BIOLEGEND |
Product Specific References | n/a |