CD243 (ABCB1, P-glycoprotein 1) Antibody from BIOLEGEND

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Antigenic SpecificityCD243 (ABCB1, P-glycoprotein 1)
CloneC494
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a, κ
Formatpurified
Size1 mL
Concentrationn/a
ApplicationsIHC-P, ICC, IP, Flow Cytometry (FC), Western Blot (WB)
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DescriptionPurified anti-CD243 (ABCB1, P-glycoprotein 1). CD243 (MDR-1) belongs to the ATP binding cassette (ABC) transporter family. With an approximate molecular mass of 170 kD, it consists of two homologous halves. Each half contains two hydrophobic transmembrane domains (TMDs) and two hydrophilic nucleotide binding domains (NBDs). The TMDs span the membrane six times, forming a chamber with a 12 transmembrane α-helix structure. NBDs drive the transport process through ATP coupling and hydrolysis and are located at the cytoplasmic face of the membra
Immunogenn/a
Other NamesP-glycoprotein 1, ABC20, CLCS, GP170, MDR1, P-GP, PGY1, colchicin sensitivity, doxorubicin resistance, multidrug resistance protein 1, ATP-binding cassette, sub-family B (MDR/TAP), member 1, MRP1, Multidrug resistance protein 1, P-glycoprotein 1
Gene, Accession #Gene ID: 5243
Catalog #907001
Price$604
Order / More InfoCD243 (ABCB1, P-glycoprotein 1) Antibody from BIOLEGEND
Product Specific ReferencesPubMed: 22833464, 8646690, 22662203, 24145283, 8674056
BIOLEGEND
BIOLEGEND
BIOLEGEND
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