Edit |   |
---|---|
Antigenic Specificity | Mouse CD279 (PD-1) |
Clone | 29F.1A12 |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2a, κ |
Format | Brilliant Violet 785™ conjugate |
Size | 50 µg |
Concentration | n/a |
Applications | Flow Cytometry (FC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Brilliant Violet 785™ anti-mouse CD279 (PD-1). CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the |
Immunogen | PD-1 cDNA followed by PD-1-Ig fusion protein |
Other Names | PD-1, Programmed Death-1, PDCD1 |
Gene, Accession # | Gene ID: 18566 |
Catalog # | 135225 |
Price | $292 |
Order / More Info | Mouse CD279 (PD-1) Antibody from BIOLEGEND |
Product Specific References | PubMed: 29429633, 31079916, 31708437, 31471106, 31810882, 32934075, 33053331, 33385331, 33838102 |