Description | PE/Cyanine7 anti-T-bet. T-bet, also known as T-box transcription factor T-bet, is considered to be a "master regulator" of Th1 lymphoid development controlling the production of the cytokine IFN-γ. T-bet is widely expressed in hematopoietic cells including stem cells, NK cells, B cells, and T cells. T-bet is critical for the control of microbial pathogens, and knockout animals show multiple physiologic and inflammatory features characteristic of asthma. T-bet expression is optimally observed after IL-12 stimulation and |
Product Specific References | PubMed: 27798619, 29091081, 30174303, 30605689, 31428465, 31269440, 31399281, 30605689, 31533031, 31350180, 30174303, 30566881, 30566881, 31704965, 32905761, 31775046, 32755573, 31747599, 33288744, 33296701, 32876566, 32640257, 33296701, 33296702, 33571429, 33711270, 33773107 |