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Antigenic Specificity | Rad50 |
Clone | W17158C |
Host Species | Rat |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | purified |
Size | 25 µg |
Concentration | n/a |
Applications | Western Blot (WB), ICC, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-Rad50. Rad50, along with MRE11 and NBS1, is a component of the MRN complex, which directly senses damaged DNA and displays multiple enzymatic functions required for non-homologous end joining. The MRN complex plays a critical role in the repair of double strand DNA breaks, meiotic recombination, and telomere maintenance in eukaryotes. Mutations in the individual components of the MRN complex give rise to genomic instability and are linked to multiple cancers and other pathological conditions. The Rad50 |
Immunogen | Partial recombinant protein corresponding to amino acid residues 1-219 of human Rad50. |
Other Names | Rad50 Double Strand Break Repair Protein, DNA Repair Protein Rad50, NBSLD |
Gene, Accession # | Gene ID: 10111 |
Catalog # | 623601 |
Price | $101 |
Order / More Info | Rad50 Antibody from BIOLEGEND |
Product Specific References | n/a |