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Antigenic Specificity | TIMP-2 |
Clone | F27P3A4 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blot (WB), IHC-P, ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Purified anti-TIMP-2. TIMP-2 (Tissue inhibitor of metalloproteinase 2) is a nonglycosylated protein that belongs to the protease inhibitor I35 (TIMP) family. Contains 1 NTR domain, predicted molecular weight 24 kD. The mechanisms of TIMPs inhibit angiogenesis appear to be specific for each member of the TIMP family. TIMP-2 binds to the surface of human endothelial cells through interaction with the integrin α3β1, and abrogates angiogenic factor induced endothelial cell proliferation in vitro and angiogenesis in vivo |
Immunogen | Ovalbumin-conjugated synthetic Peptide DSGNDIYGNPI |
Other Names | Metalloproteinase inhibitor 2, Tissue inhibitor of metalloproteinases 2, TIMP2 |
Gene, Accession # | Gene ID: 7077 |
Catalog # | 635402 |
Price | $229 |
Order / More Info | TIMP-2 Antibody from BIOLEGEND |
Product Specific References | PubMed: 18757369 |