IRF3 Antibody from BIOLEGEND
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| Antigenic Specificity | IRF3 |
| Clone | 12A4A35 |
| Host Species | Mouse |
| Reactive Species | human, mouse |
| Isotype | IgG2b, κ |
| Format | purified |
| Size | 100 µg |
| Concentration | n/a |
| Applications | Western Blot (WB), ChIP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Purified anti-IRF3. IRF-3 is a member of the interferon regulatory transcription factor (IRF) family. It mediates interferon-stimulated response element (ISRE) promoter activation and functions as a molecular switch for antiviral activity. DsRNA generated during the course of a viral infection leads to IRF-3 phosphorylation on the C-terminal serine/threonine cluster. This induces a conformational change, leading to its dimerization, nuclear localization and association with CREB protein binding to dsRNA-activated f |
| Immunogen | Partial IRF-3 recombinant protein (200-427 a.a.) |
| Other Names | Interferon regulatory factor-3 (IRF-3) |
| Gene, Accession # | Gene ID: 3661 |
| Catalog # | 655702 |
| Price | $265 |
| Order / More Info | IRF3 Antibody from BIOLEGEND |
| Product Specific References | PubMed: 28591144, 28591144 |
BIOLEGEND
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