Description | PE/Cyanine7 anti-mouse CD86. CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activatio |
Product Specific References | PubMed: 21807014, 23747738, 26847186, 27523746, 27448584, 27847326, 27926930, 27569659, 27523746, 29326695, 29402982, 29336888, 30546010, 30796212, 31042472, 31120187, 31109957, 31509749, 31042472, 30850233, 32001710, 32195350, 32132528, 32117241, 32358491, 32402289, 31693894, 31747599, 29330512, 32923129, 33136000, 32640259 |